Both are well-made, Japanese high school movies with the same male lead actor, Yamazaki Kento. Both have themes of friendship, loneliness and finding one self and one's place in the world.

Both encompass the same style and feel of the older Korean rom-coms with a bit silly and unique but determined female leads and cool but a bit aloof/proud male leads.

Both movies have a serene, slice-of-life theme with strong female characters and beautiful Japanese scenery, with the depiction of little wonders and obstacles of the everyday lives.

Both dramas are realistic historical dramas, focused heavily on the details and customs of the time and place (Korea's Joseon dynasty), both drawing inspiration from real historical figures. They can both be categorized as medical dramas (although Jewel in the Palace's main genres are also food and the royal palace/court), both focused on character growing and the main characters' career paths as well as development of medicine in general (more so in Jejoongwon). Both have brave, intelligent and persistent main characters, as well as strong female characters.

Compared to Jewel in the Palace which is set in 16th century, more in the beginning of Joseon dynasty, Jejoongwon is set some hundreds years later when Korea's Joseon dynasty is drawing near and Western medicine is gaining foothold in the country for the first time.

Jewel in the Palace is historically accurate, well-made, big budget drama that was and still is, one of the most popular and most well-reviewed sageuks that shows the life of the royal court through the eyes of a servant and concentrates on the strict hierarchical system of the Joseon dynasty especially from the female point of view. The production value of Jejoongwon is not as good as in Jewel in the Palace but it has a good script, great characters and interesting themes (the rapid development of medicine, Korea's final dynasty drawing near, Korea opening to the West and Japan, the dynasty's strict hierarchical system crumbling and so on).